Pluripotency is depicted by a self-renewing state that can competently differentiate to form the three germ layers.Different stages of early murine development can be captured on a petri dish, delineating a spectrum of pluripotent states, ranging from embryonic stem cells, embryonic germ cells to epiblast stem cells.Anomalous cell populations displ
Compact Ultramassive Antenna Array (CUMA) is a pioneering paradigm that leverages the flexibility of the Fluid Antenna System (FAS) to enable a simple multiple access scheme for massive connectivity without the need for precoding, power oakley fives 4.0 control at the base station or interference mitigation in each user’s equipment.In order
Summary: BRCA1 promotes homologous recombination (HR) by activating DNA-end resection.By contrast, 53BP1 forms a barrier that inhibits DNA-end resection.Here, we show that BRCA1 promotes DNA-end resection by relieving the 53BP1-dependent barrier.We show that 53BP1 is phosphorylated by ATM in S/G2 phase, promoting RIF1 recruitment, which inhibits re
Idiopathic pulmonary fibrosis (IPF) is a chronic, irreversible, and progressive interstitial lung disease characterized by recurrent alveolar epithelial cell injury, fibroblast hyperproliferation, and cumulative deposition of extracellular matrix leading to alveolar destruction in the lungs.Mitotic arrest deficient 2 like 1 (MAD2L1) is a component